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Protazen's formula is designed to:
Support a positive outlook
Improve emotional well-being
Improve mental clarity
Increase energy during the day
Sharpen short and long-term
memory
Relax the body at night in order
to induce a normal sleep
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*Although the FDA has deemed our ingredients safe for sale as dietary supplements, these statements have not been evaluated by the Food and Drug
Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.  This site is intended for informational purposes only and should
not be interpreted as specific medical advice. If you have a specific medical condition or take particular medication, it is best that you consult with a medical
professional before beginning any new supplement regimen (including Protazen).
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"SAM-e"

Supporting Research and Studies

  1. Braverman E, “The healing nutrients within/Eric R.
    Braverman.” 3rd ed. Print
  2. Andreoli VM, Maffei F, Tonon GC. “S-adenosyl-L-methionine
    (SAMe) blood levels in schizophrenia and depression.”
    Monogr Gesamtgeb Psychiatr Psychiatry Ser. 1978; 18: 147-
    50.
  3. Curcio M, Catto E, Stramentinoli G, Slgeri S. “Effects of S-
    adenosyl-L-methionine on serotonon metabolism in rat
    brain.” Prog Neuropsychopharmacol. 1978; 2(1): 65-71.
  4. Czyrak A, Rogoz Z, Skuza G. “ Antidepressnat activity of S-
    adenosyl-L-methionine in mice and rats.” J Basic Clin
    Physiol Pharmacol. 1992; 3(1): 1-17.
  5. Fava M, Rosenbaum JF, MacLaughlin R. “Neuroendocrine
    effects of S-adenosyl-L-methionine, a novel putative
    antidepressant.” J Psychiatr Res. 1990; 24(2): 177-184.
  6. Losada ME, Rubio MC. “Acute effects of S-adenosyl-L-
    methionine in catecholaminergic central function. Eur J
    Pharmacol. 1989; 163(2-3): 353-356.
  7. Otero-Losada ME, Rubio MC. “Acute changes in 5-ht
    metabolism after S-adenosyl-L-methionine” Gen Pharmacol.
    1989; 20(4): 403-406.
  8. Crellin R, Bottiglieri T, Reynolds EH. “Folates and
    psychiatric disorders. Clinical potential.” Drugs 1993; 45(5):
    623-636.
  9. Janicak PG, Lipinski J, Davis JM. “S-adenosylmethionine in
    depression. A literature review and preliminary report.” Ala J
    Med Sci. 1988; 25(3); 306-313.
  10. Bell KM, Plon L, Bunney WE, Potkin SG. “S-
    adenosylmethionine treatment of depression: a controlled
    clinical trail.” Am J Psychiatry. 1998; 145(9); 1110-1114.
  11. Bell KM, Potkin SG, Carreon D, Plon L. “S-
    adenosylmethionine blood levels in major depression:
    changes with drug treatment.” Acta Neurol Scand Suppl.
    1994; 154: 15-18.
  12. De Vanna M, Rigamonti R. “Oral S-adenosyl-L-methionine in
    depression.” Current Therapeutic Research 1992; 52(3):
    478-485.
  13. Oral S-adenosyl-L-methionine for Treatment of Depression,
    Osteoarthritis, and Liver Disease. www.ahrq.gov
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